Carlos Santana

Las Vegas, 2012-present

Residency: An Intimate Evening with Santana: Greatest Hits Live, presented by SiriusXM
Venue: House of Blues at Mandalay Bay
Opened at House of Blues: May 2012
Before House of Blues: Two years at the Joint at the Hard Rock Hotel
Years running: In its 14th year as of the 2026 dates
2026 dates: January-February, May, September and November 2026; shows at 8 p.m.
Venue listing: House of Blues Las Vegas lists a Santana show on November 4, 2026
Charity: Part of ticket proceeds go to his Milagro Foundation (created 1998) and House of Blues' Music Forward Foundation
Band: Includes his wife, drummer Cindy Blackman Santana

About

Carlos Santana has been one of the Strip's steadiest headliners for well over a decade. He first spent two years at the Joint at the Hard Rock Hotel, where, the Las Vegas Weekly reported, 3,000 fans had assigned seats and a giant LED screen played footage of his career. In May 2012 he moved to House of Blues at Mandalay Bay with a show billed as An Intimate Evening with Santana: Greatest Hits Live, initially as a two-year residency.

The smaller room changed the feel. The Weekly's 2012 review described House of Blues as more like a big club, with a general-admission floor and the band close enough to feel. The show itself is built on his catalog, from "Black Magic Woman" and "Evil Ways" to "Smooth" and "Maria Maria," with long improvised solos. His wife, drummer Cindy Blackman Santana, plays in the band. Santana told the Review-Journal, "We keep it fresh. We do not regurgitate nostalgia."

The two-year booking never really ended. Santana's own site described the 2026 dates as the residency's 14th year at House of Blues, and he has added runs in January and February, May, September and November 2026, all at 8 p.m. Part of every ticket goes to the Milagro Foundation, which Santana and his family started in 1998 to support children's arts, education and health, and to House of Blues' Music Forward Foundation. Santana has said he will not announce a farewell: "When I'm done, I'm not even going to tell anybody."

What to expect

The residency is current. House of Blues Las Vegas's own site lists "SiriusXM Presents An Intimate Evening with SANTANA Greatest Hits Live" in its Music Hall on Wednesday, November 4, 2026, part of a November run that Fox5 reported as November 4, 5, 7, 8, 11, 12, 14 and 15. House of Blues is inside Mandalay Bay.

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Good to know

Capacity reports differ: the Las Vegas Weekly put House of Blues at a little more than 1,200 in 2012, while Las Vegas Magazine called it an 1,800-capacity venue in 2025.
General-admission tickets started at $89 when the House of Blues run opened in 2012, according to the Las Vegas Weekly; check current prices with the venue.
Citi cardholders and fan-club members usually get presale access before the general on-sale, per the 2026 announcements.
House of Blues is part of Mandalay Bay, an MGM Resorts property.

Questions about Carlos Santana

Is Carlos Santana still playing Las Vegas?

Yes. His residency, An Intimate Evening with Santana: Greatest Hits Live, continues at House of Blues inside Mandalay Bay. The venue's own site lists a show on November 4, 2026, and Fox5 reported November dates on the 4th, 5th, 7th, 8th, 11th, 12th, 14th and 15th, all starting at 8 p.m.

How long has Santana played House of Blues?

Since May 2012, when he opened what was announced as a two-year residency there. Santana's official site described the 2026 dates as the residency's 14th year at House of Blues. Before that he played two years at the Joint at the Hard Rock Hotel.

What songs does Santana play in Las Vegas?

The show is a greatest-hits set. Las Vegas Magazine and the Review-Journal mention "Black Magic Woman," "Evil Ways," "Jingo," "Oye Como Va," "Smooth" and "Maria Maria," with long improvised solos. His wife, drummer Cindy Blackman Santana, is part of the band, and Santana has said the goal is to keep each show fresh rather than nostalgic.

Where is House of Blues in Las Vegas?

House of Blues Las Vegas is inside Mandalay Bay Resort and Casino, and Santana's show plays its Music Hall. Tickets are sold through House of Blues, Mandalay Bay and Ticketmaster. When the run moved there in 2012, the Las Vegas Weekly described the room as feeling like a big club, with a general-admission floor close to the stage.

Does Santana's Las Vegas show support a charity?

Yes. A portion of proceeds from every ticket benefits the Milagro Foundation, which Carlos Santana and his family created in 1998 to help children in arts, education and health, and the House of Blues Music Forward Foundation, according to Fox5.